Alligator Bioscience

Encouraging clinical safety data for ATOR-1017

The Phase I study with ATOR-1017 has progressed exceptionally well and in August we presented interim data that showed a good safety profile at clinically relevant dose levels. The dose evaluation will continue with yet higher doses and we expect to present safety and potentially efficacy data from the entire study in the spring of 2021. At the same time, we have shown strong Proof of Mechanism data for mitazalimab, while the ATOR-1015 program reported side effects at high dose levels.The nature of the reactions have lead to a need to re-design the planned clinical trial in malignant melanoma and to perform additional preclinical investigations. We will now focus our clinical investments to ATOR-1017 and mitazalimab. Both programs have first-in-class potential, and will move into clinical Phase II during 2021″, commented CEO Per Norlén.

Promising safety data for ATOR-1015
“With the new strategy announced in early April, we have put a stronger focus on Alligator’s clinical development portfolio. ATOR-1015 has received a great deal of attention in connection with the positive interim data presented at AACR and ASCO, the world’s two largest oncology conferences. We have also worked actively with business development and signed a research agreement with Scandion Oncology during the period, while our collaboration with Biotheus developed well and led to an additional milestone payment. The Covid-19 pandemic has been stressful but has not led to any serious delays in the clinical projects. We are now looking forward to an exciting second half of 2020 for Alligator”, commented CEO Per Norlén.

Stronger focus on clinical projects “The focusing of our operations protects the company’s liquidity, but is also part of our long-term strategy with a emphasis on clinical projects and innovation,” CEO Per Norlén comments. Significant events January-March • Andreas Johannesson was appointed interim CFO. • The COVID-19 pandemic impacts the recruitment of new patients to […]

Lund, Sweden, 2 March 2020 – Alligator Bioscience (Nasdaq Stockholm: ATORX), a biotechnology company developing antibody-based pharmaceuticals for tumor-directed immunotherapy, announced today that the Swedish version of the Annual Report 2019 is available on the company website http://www.alligatorbioscience.com. An English version will follow shortly. For further information, please contact: Cecilia Hofvander, Director Investor Relations & […]

“2019 was the year when Alligator entered the clinical phase on a broad front. At the beginning of the year, we had one clinical project and at year-end, the number had increased to four”, commented CEO Per Norlén.

“We are now regaining the exclusive, global rights to develop and commercialize ADC-1013 and at the same time receive enough ADC-1013 substance to, with or without a new partner, bring ADC-1013 into Phase II clinical trials next year. In total, we now have three projects in clinical development, and soon another one where the first […]

Competitive safety data for ADC-1013.

First patient dosed in Phase I clinical study of ATOR-1015

Lund, Sweden, 22 March 2019 – Alligator Bioscience (Nasdaq Stockholm: ATORX), a biotechnology company developing antibody-based pharmaceuticals for tumor-directed immunotherapy, announced today that the Annual Report 2018 is available at the company website http://www.alligatorbioscience.com. For further information, please contact:Cecilia Hofvander, Director Investor Relations & CommunicationsPhone +46 46 540 82 06E-mail: cecilia.hofvander@alligatorbioscience.com. This information is such information […]

The bispecific drug candidate ATOR-1015 in clinical development