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Alligator Bioscience

Alligator Bioscience

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Start > Research and development > Scientific publications
  • Scientific publications
  • Immunotherapy of cancer
  • Pipeline
  • Technology platform
  • Scientific advisors and collaborators
  • The CTLA-4 x OX40 bispecific antibody ATOR-1015 induces anti-tumor effects through tumor-directed immune activation
    Anne Månsson Kvarnhammar, Niina Veitonmäki, Karin Hägerbrand, Mia Thagesson, Doreen Werchau, Kristine Smedenfors, Anna Dahlman, Anna Rosén, Maria Johansson, Ida Åberg, Per Norlén, Christina Furebring and Peter Ellmark., SITC 9 November 2018
  • ATOR-1017, a tumor directed Fcγ-receptor cross-linking dependent ATOR-1017, a tumor directed Fcγ-receptor cross-linking dependent
    Karin Enell Smith, Anna Rosén, Anna Dahlman, Karin Barchan, Ida Åberg, Doreen Werchau, Mia Thagesson, Niina Veitonmäki, Christina Furebring and Peter Ellmark., SITC 9 November 2018
  • Potent Tumor-Directed T cell Activation and Tumor Inhibition Induced by a 4-1BB x 5T4 ADAPTIR™ Bispecific Antibody
    Michelle Nelson, Gabriele Blahnik-Fagan, Robert Bader, Doreen Werchau, Anneli Nilsson, Lill Ljung, Jeannette Bannink, Danielle Mitchell, Lynda Misher, Catherine McMahan, David Bienvenue, Maria Askmyr, Anna Dahlman, Peter Ellmark, Gabriela Hernandez-Hoyos and Sara Fritzell. , SITC 9 November 2018
  • ATOR-1017; a 4-1BB antibody designed for superior safety/efficacy profile in cancer immunotherapy
    Eva Dahlén, Anna Rosén, Adnan Deronic, Karin Barchan, Anna Dahlman, Peter Ellmark, Tina Furebring and Karin Enell Smith, 4th CRI-CIMT-EATI-AACR International Cancer lmmunotherapy Conference September 30, 2018
  • The agonistic CD40 antibody improves T cell responses and delays growth of a syngeneic tumor in an ovalbumin vaccination model
    Adnan Deronic, Anneli Nilsson, Mia Thagesson, Doreen Werchau, Niina Veitonmäki, Per Norlén, Christina Furebring and Peter Ellmark, World Preclinical Congress June 2018
  • CTLA-4 x OX40 bispecific antibody ATOR-1015 induces anti-tumor effects through tumor-directed immune activation
    Anne Månsson Kvarnhammar, Niina Veitonmäki, Karin Hägerbrand, Mia Thagesson, Doreen Werchau, Kristine Smedenfors, Anna Rosén, Maria Johansson, Per Norlén, Christina Furebring and Peter Ellmark, Poster CIMT 16 May 2018
  • Tumor Antigen-dependent T Cell Activation And Tumor Localization Induced By A Novel 4-1BB X 5T4 ADAPTIR™ Bispecific Antibody
    Sara Fritzell, Doreen Werchau, Maria Askmyr, Niina Veitonmäki, Anneli Nilsson, Adnan Deronic, Mia Thagesson, Anna Säll, Laura von Schantz, Robert Bader, Gabriele Blahnik-Fagan, Michelle Nelson, David Bienvenue, Gabriela Hernandez-Hoyos, Peter Ellmark , Poster CIMT 16 May 2018
  • Activation of the CD137 Pathway in T cells by a CD137 x 5T4 bispecific ADAPTIR™ Molecule Requires Co-engagement of CD137 and 5T4
    Gabriele Blahnik-Fagan, Robert Bader, Jeannette Bannink, Danielle Mitchell, Lynda Misher, Cathy McMahan, David Bienvenue, Laura von Schantz, Eva Lindqvist, Doreen Werchau, Anneli Nilsson, Maria Askmyr, Niina Veitonmäki, Sara Fritzell, Peter Ellmark, Michelle Nelson1, and Gabriela Hernandez-Hoyos, Poster AAI 5 May 2018
  • Design and Generation of Bispecific Antibodies for Immuno-Oncology
    von Schantz L, Säll A, Carlsson F, Thorulffsson M, Petersson J, Tsiobanelis K, Nyesiga B, Jansson K, Rosén A, Hägerbrand K, Dahlman A, Månsson-Kvarnhammar A, Veitonmäki N and Furebring C., Poster PEGS 2 May 2018
  • Screening, Optimization and Characterization of a Novel 4-1BB x 5T4 ADAPTIR™ Bispecific Antibody
    von Schantz L, Misher L, Mitchell D, Gruswitz F, Woodruff B, Daugherty M, Aguilar M, Huntington K, Bader R, Blahnik-Fagan G, Säll A, Werchau D, Thagesson M, Nilsson A, Deronic A, Askmyr M, Veitonmäki N, Fritzell S, Ellmark P, Hernandez-Hoyos G and Bienvenue D., Poster PEGS 2 May 2018
  • CTLA-4 x OX40 bispecific antibody ATOR-1015 induces anti-tumor effects through tumor-directed immune activation
    Veitonmäki N, Månsson Kvarnhammar A, Fritzell S, Enell Smith K, Thagesson M, Werchau D, Hägerbrand K, Rosén A, Johansson M, Norlén P, Furebring C, Ellmark P, Poster AACR 17 April 2018
  • Bispecific antibodies in cancer immunotherapy
    Eva Dahlén, Niina Veitonmäki and Per Norlén , Therapeutic advances in vaccines and immunotherapy, 2018, Vol. 6(1) 3–17,

About

Alligator develops antibody-based pharmaceuticals for cancer treatment. The company specializes in the development of tumor-directed immunotherapies, in particular agonistic mono- and bispecific antibodies. The company is active in the early stages of drug development, from idea to clinical phase II studies.

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Alligator Bioscience AB
Medicon Village
Scheelevägen 2
SE-223 81 Lund
Sweden

Phone: + 46 (0)46 540 82 00

info@alligatorbioscience.com
ir@alligatorbioscience.com

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